HowardNeuroLab@kevinmawright And the problem with C57s is that they're frail and stupid? Have you ever seen... mice? Or worms or flies or fish? In 2022 are we still complaining about animal models, let alone splitting hairs about mouse strains? Use the most valid model that best suits your research.
HowardNeuroLab@kevinmawright Penetrance. One person with a mutation can have devastating phenotypes while a close family member with the same mutation is normal. With C57 mice we can study the cell/circuit changes. By outcrossing them, understand genetic interactions. That's how our disease/mice work.
MadScientistPhDFaculty survival tip: got an email from administration you don’t want to deal with? If there’s a link inside, report it to IT as a phishing attempt. This saves you time and energy while at the same time pitting the administration and IT against each other. WIN WIN!!