@article {420,
	title = {Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria.},
	journal = {Cell},
	volume = {73},
	number = {1},
	year = {1993},
	month = {1993 Apr 9},
	pages = {133-46},
	abstract = {Group II introns al1 and al2 of the yeast mtDNA cox1 gene encode reverse transcriptase-like proteins that function in RNA splicing and may play a role in intron mobility and excision. We find that ribonucleoprotein particles from yeast mitochondria contain a reverse transcriptase activity that is likely encoded by al1 and al2 and is highly specific for the introns and their flanking exons. Using a mutant strain with elevated activity, we show that the reverse transcriptase uses either excised intron RNA or cox1 pre-mRNA as template and initiates cDNA synthesis near the 3{\textquoteright} end of al2 and immediately downstream in E3. Our results suggest that introns al1 and al2 are retroelements, which encode reverse transcriptases that have adapted to function in RNA splicing.},
	keywords = {Base Sequence, DNA Transposable Elements, Exons, Introns, Mitochondria, Molecular Sequence Data, Nucleic Acid Conformation, Regulatory Sequences, Nucleic Acid, Ribonucleoproteins, RNA-Directed DNA Polymerase, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Transcription, Genetic},
	issn = {0092-8674},
	author = {Kennell, J C and Moran, J V and Perlman, P S and Butow, R A and Lambowitz, A M}
}
