@article {439,
	title = {A group II intron in the Neurospora mitochondrial coI gene: nucleotide sequence and implications for splicing and molecular evolution.},
	journal = {Nucleic Acids Res},
	volume = {17},
	number = {22},
	year = {1989},
	month = {1989 Nov 25},
	pages = {9087-99},
	abstract = {The temperature-sensitive Neurospora nuclear mutant cyt18-1 is deficient in splicing many Group I mitochondrial introns when grown at its non-permissive temperature; however, splicing of intron 1 in the coI gene of the Adiopodoume (formerly called North Africa) strain is unaffected (R.A. Collins and A.M. Lambowitz, J. Mol. Biol. 184: 413-428, 1985). Here we show that coI intron 1 is a typical Group II intron, the only one identified to date in Neurospora. The differential effect of the cyt18-1 mutation suggests that splicing of certain introns could be regulated independently of others by nuclear-encoded proteins. The intron contains a long open reading frame (ORF) resembling that of the Neurospora Mauriceville mitochondrial plasmid. The intron and plasmid ORFs share unusual features of codon usage that suggest both evolved outside of the Neurospora mitochondrial genetic system.},
	keywords = {Amino Acid Sequence, Base Sequence, Biological Evolution, Exons, Genes, Fungal, Introns, Molecular Sequence Data, Mutation, Neurospora, Neurospora crassa, Nucleic Acid Conformation, Plasmids, Restriction Mapping, RNA Splicing, Sequence Homology, Nucleic Acid},
	issn = {0305-1048},
	author = {Field, D J and Sommerfield, A and Saville, B J and Collins, R A}
}
