@article {466,
	title = {The [poky] mutant of Neurospora contains a 4-base-pair deletion at the 5{\textquoteright} end of the mitochondrial small rRNA.},
	journal = {Proc Natl Acad Sci U S A},
	volume = {81},
	number = {12},
	year = {1984},
	month = {1984 Jun},
	pages = {3791-5},
	abstract = {[ poky ] and other group I extranuclear mutants of Neurospora crassa are characterized by gross deficiencies of mitochondrial small ribosomal subunits and small (19S) rRNA. Blot-hybridization and other experiments suggest that the 19S rRNA (2.0 kilobases) is synthesized via precursors that contain 5{\textquoteright}-end extensions. The ratio of precursors to mature rRNA is higher in [ poky ] and other group I mutants than in wild type, indicating that the defect involves impaired processing and/or instability of 19S rRNA. [ poky ] and other group I mutants contain a 4-base-pair deletion in the coding sequence for the mitochondrial small rRNA, just downstream from what would normally be the 5{\textquoteright} end of the rRNA. This deletion apparently results in synthesis of aberrant 19S rRNAs that are missing 38-45 nucleotides from their 5{\textquoteright} ends. We propose that the 4-base-pair deletion is the primary defect in [ poky ] and other group I extranuclear mutants.},
	keywords = {Base Sequence, Chromosome Deletion, DNA, Mitochondrial, Mutation, Neurospora, Neurospora crassa, Nucleic Acid Conformation, RNA Processing, Post-Transcriptional, RNA, Ribosomal},
	issn = {0027-8424},
	author = {Akins, R A and Lambowitz, A M}
}
