Current research of the Ippolito Lab utilizes molecular and proteomic techniques for the comprehensive profiling of antibody repertoires in human adaptive immune responses. The method is a synergistic combination of (i) IgG immunoglobulin protein mass spectrometry and (ii) a high-throughput DNA sequencing method that preserves the natural pairing of B-cell heavy and light chain variable regions (VH:VL regions). This innovation allows for the direct comparison of protein-level plasma IgG immunoglobulin repertoires to DNA-level
Dr. Shelley M. Payne, LCID Director, was among three experts recently interviewed by Healthline.com about studies looking at COVID-19 breakthrough infection risk with the Omicron variant. She said that while studies on neutralizing antibodies against the variant are useful, scientists will also need to look at real-world data on
Cienegas, as defined here, are wetlands in arid and semi-arid regions associated with groundwater or lotic components that ideally result in perennial waters on temporal scales of decades to centuries. Cienegas are typically no lower than 0 m, and higher than 2000 m, rarely lower but sometimes higher elevation localities occur. Cienegas are typified by significant differences in flora and fauna relative to the greater terrestrial conditions in the region in which it is located. Cienegas are freshwater to brackish North American wetlands associated with fluvial systems of arid/semi-arid areas of the southwestern U.S. and northwestern Mexico. Once extensively utilized by the region's indigenous human cultures, early European explorers and settlers, the extent of these aquatic riparian communities has dramatically decreased from historic conditions and the community is now considered imperiled in North America. This dataset provides location information and some limited attributes of cienegas in the southwestern U.S. and northern Mexico. There is no information as to the size of the cienega and other important attributes.
The LaMontagne Center for Infectious Disease was established at The University of Texas at Austin in November 2013 as the Center for Infectious Disease (CID) and was renamed just over three years later for scientist and public health champion John Ring LaMontagne. The LaMontagne Center, while located within the College of Natural Sciences, is composed of highly interdisciplinary researchers spanning at least four colleges: Natural Sciences, Engineering, Pharmacy, and the Dell Medical School.
The LaMontagne Center conducts basic and translational research into the
The LaMontagne Center for Infectious Disease is the first interdisciplinary research center on a Tier One research university campus that aims to bridge the gap between basic and translational research into microbial and viral pathogenesis.
The LaMontagne Center consists of members from four distinct areas within the University: (1) The College of Natural Sciences, (2) The Cockrell School of Engineering, (3) The School of Pharmacy, and (4) The Dell Medical School.
Members bring expertise and research in over 30 different diseases including Coronaviruses,
The mission of the John Ring LaMontagne Center for Infectious Disease is to bridge the gap between basic and translational research into microbial and viral pathogenesis. These efforts include characterizing and predicting the spread of infectious diseases through populations, and supporting programs to define the human and animal responses to challenge by infectious agents and how human genetics impact susceptibility to infection. Our primary goals are:
To create a center of national prominence in infectious diseases.
NPR and The Atlantic magazine recently interviewed Dr. Lauren Ancel Meyers, LCID Affiliate Member and Director of the UT COVID-19 Modeling Consortium, regarding possible outcomes of the Omicron COVID-19 variant in the United States. Dr. Meyers specifically discussed with both media outlets the
The discovery of silencing non-coding RNAs has dramatically changed our understanding of the regulation of gene expression. This has opened up a new area in the regulation of the immune response. The Sullivan Lab's research focuses on understanding the role of non-coding RNAs in virus infection and host defense pathways. Researchers work with an array of diverse virus families including DNA tumor viruses and RNA viruses, as well as the enzyme DUSP11. DUSP11 is an RNA phosphatase that helps to regulate the innate immune response. The
The Smyth Lab research composes of Drug Delivery, Formulation Science, and Pharmaceutical Engineering. Researchers focus on the development of novel methods for drug delivery including inhalation, nasal, transdermal, ophthalmic, and oral delivery systems for a variety of diseases. Translation of these technologies to the clinic is the long-term goal of the Lab and is supported by developing a mechanistic understanding of the complex physical and biological systems.
