May 2023

FDA Approves RSV Vaccine Utilizing McLellan and NIH Research

May 30, 2023

The Food and Drug Administration recently approved the first-ever respiratory syncytial virus (RSV) vaccine for older adults that utilizes research developed by a team that includes LCID Member Jason McLellan and scientists at the National Institutes of Health (NIH). This vaccine culminates a decades-long search for an effective tool to prevent this illness which can be deadly to children and older adults.

McLellan, along with NIH researchers Barney Graham and Peter Kwong, has been working for several years on structure-based vaccine design

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faculty

Welcoming New Topology Faculty Fall 2023

May 28, 2023

We are delighted to welcome Anthony Conway, Irving Dai, Maggie Miller, and Lisa Piccirillo to our tenure stream faculty. The research areas of our new colleagues are in Topology, and they will arrive at UT in Fall 2023. Anthony Conway is joining us from a postdoctoral appointment at MIT. Irving Dai is joining us from an NSF postdoctoral appointment at Stanford University. Maggie Miller was awarded a Maryam Mirzakhani New Frontier Award in 2023, and a Clay Research Fellowship in 2021. She is currently a Clay Fellow at Stanford University. Lisa Piccirillo was awarded a Maryam

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NVIDIA GPU

Fitting an NVIDIA 4090 in a 1-U server

May 25, 2023
Thanks to our generous funders, we purchased a 1-U rackmount server. It is a supermicro server with a 64-core AMD chip and 45TB zfs raid array. The primary use is hosting our PostGIS-enabled database. We wanted to train some neural networks and so purchased an NVIDIA 4090 GPU. The question is how to connect it to a 1-U server chasis. The solution I came up with is to run a PCIe cable out the back and attach the GPU externally with its own power supply. The blocker was that I did not know that the PSU will not power up without being plugged into a motherboard. In the end, I figured out that I Read more about Fitting an NVIDIA 4090 in a 1-U server
RD Slocum, H Wang, A. Tomasevich, Greg Clark, and Stanley J Roux. “Role of apyrase in salvaging of phosphate from extracellular nucleotides and in regulating phosphate uptake in Arabidopsis. .” Preprint of article submitted. Abstract

Apyrases are NTPDases that remove the terminal phosphate from NTPs and NDPs, but not from NMPs. They have conserved structures and functions in yeast, plants and animals. Among the most studied APYs in plants are those in Arabidopsis (AtAPYs) and peas (PsAPYs), both of which have been shown to play major roles in regulating plant growth and development. Valuable insights on their functional roles have been gained by transgenically altering their transcript abundance, either by constitutively expressing them or by their suppression. This review focuses on studies of transgenic lines of yeast and multiple different plants that revealed insights on the growth-altering functions of plant apyrases in different organisms. APY expression can also be inhibited post-translationally by chemically blocking its enzymatic activity, so this review also briefly covers studies that used inhibitors to suppress APY activity in plants and fungi.

Mould and Damp: The Dangerous Health Risks You Need to Know About

It's easy to come across damp and mould in our daily lives, especially in indoor environments such as our homes and workplaces. However, what we often forget is the serious health risks associated with these seemingly minor disrepairs. Here are some facts you need to know.

The Risks of Mould and Damp

Mould and damp can release tiny spores into the air that can trigger allergic reactions and respiratory problems. These spores can also release mycotoxins, which are toxic compounds that can cause a range of health problems

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