Dr. James R. Walker

My research interests include the mechanism by which the bacterial chromosome is replicated, how replication is controlled, and how replication is integrated with cell division. Specifically, we study components of the Escherichia coli replicative polymerase, DNA polymerase III, the specific functions of some of the subunits of this ten-protein complex, and how the genes which encode these subunits are expressed and regulated. Also under study is the mechanism by which a