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Lambowitz Lab
Department of Molecular Biosciences
100 East 24th St., Stop A5000
Austin, TX 78712
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Protocols
Total RNA-seq protocol using thermostable group II intron reverse transcriptases (TGIRTs)
Small RNA-seq/CircLigase protocol using thermostable group II intron reverse transcriptases (TGIRTs)
Total ssDNA-seq protocol using thermostable group II intron reverse transcriptases (TGIRTs)
Recent Publications
Mechanisms used for cDNA synthesis and site-specific integration of RNA into DNA genomes by a reverse transcriptase-Cas1 fusion protein
Abstract PO4-23-11: Resistance Mechanisms to CDK4/6 Inhibitors and/or Tamoxifen Using Comprehensive Thermostable Group II Intron Reverse Transcriptase Sequencing
Biochemical and structural insights into a 5’ to 3’ RNA ligase reveal a potential role in tRNA ligation
Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation
Inflammatory breast cancer biomarker identification by simultaneous TGIRT-seq profiling of coding and non-coding RNAs in tumors and blood
Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2
Group II-like Reverse Transcriptases Function in Double Strand Break Repair
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