Lydia was a graduate student and the first to receive her Ph.D in the Sullivan Lab. She then went on to be a Program Director at the NSF and currently is at VP Research Bridge Partners.

Project description:

I study how human herpesvirus 8 (KSHV) interacts with the host cell through transcriptional and translational regulatory mechanisms. This work has the goal to help elucidate how KSHV is able to hide from the immune system after infection, effectively limiting treatment options.

Biography:

B.A., June 2006, Carleton College, Northfield, Mn; Major in Biology; Concentration in Biochemistry.

Gottlieb Lecture Series Committee, University of Texas, Austin, Tx.

Ph. D. Cell and Molecular Biology

Selected Publications:

McClure LV. Disease therapies through RNAi. [senior thesis]. Northfield (MN): Carleton College; 2006

McClure LV, Blakely EA & Bjornstad KA. Radiation effects on Connexin 50 expression in human lens epithelial cells. [abstract]. U.S. Department of Energy Journal of Undergraduate Research. 2006; VI: 131.

McClure LV & Sullivan CS. Kaposi’s sarcoma herpes virus taps into a host microRNA regulatory network [preview]. Cell Host Microbe. 2008 Jan 17; 3(1): 1-3.

McClure LV, Lin YT & Sullivan CS. Antiviral RNAi: Concepts, Methods, and Applications: Detection of viral miRNAs by Northern blot. Methods Mol Biol. 2011; V: 271.

McClure LV, Seo GJ and Sullivan CS, 2011, Reporter-based Assays for Analyzing RNA Interference in Mammalian Cells. In Methods in Molecular Biology: “Argonaute Proteins: Methods and Protocols”, T. C. Hobman and T. Duchaine, Editors. Humana Press. (invited book chapter). 

Presentations:

McClure, LV, Blakely, EA, Bjornstad, K & Rosen, C. Radiation effects on Connexin 50 expression in human lens epithelial cells. [poster] Lawrence Berkeley National Laboratory Summer Poster Session (2005).

McClure, LV & Sullivan CS. SV40 infection induces increased levels of a host non-coding RNA. [poster]  Molecular Biology of DNA Tumor Virus Conference. Madison, WI (2008).  

McClure, LV & Sullivan CS. A possible widespread virus immune evasion strategy by Cis element-mediated transcript regulation. [talk] American Society for Microbiology South Texas Branch Meeting. Texas State University (2010).

“When I'm not in the lab you will most-likely find me running around town.”

One of my favorite pieces of data: