Publications 2005 - 2010

#228 - Enhancement of Ultraviolet Photodissociation Efficiencies through Attachment of Aromatic Chromophores

Vasicek, L., Brodbelt, J.S.
Anal. Chem
Volume 82, 2010. Pages 9441-9446.

#227 - Ultrafast Ultraviolet Photodissociation at 193 nm and its Applicability to Proteomic Workflows

Madsen, J., Boutz, D., Brodbelt, J.S.
J. Proteome Research
Volume 9, 2010. Pages 4205-4214.

#226 - Preferential Cleavage of N-N Hydrazone Bonds for Sequencing Bis-arylhydrazone Conjugated Peptides by Electron Transfer Dissociation

Gardner, M., Brodbelt, J.S.
Anal. Chem
Volume 82, 2010. Pages 5757-5759.

#225 - Characterization of Oligodeoxynucleotides and Modifications by 193 nm Photodissociation and Electron Photodetachment

Smith, S.I., Brodbelt, J.S.
Anal. Chem
Volume 82, 2010. Pages 7218-7226.

#224 - Investigation of the Reactivity of Oligodeoxynucleotides with Glyoxal and KMnO4 Chemical Probes by Electrospray Ionization Mass Spectrometry

Parr, C., Pierce, S., Smith, S.I, Brodbelt, J.S.
Int. J. Mass Spectrom
Volume 304, 2010. Pages 115-123.

#223 - Transmission-mode direct analysis in real time and desorption electrospray ionization mass spectrometry of insecticide-treated bednets for malaria control

Perez, J J.; Harris, GA.; Chipuk, J E.; Brodbelt, J.S., Green, M D.; Hampton, C Y.; Fernandez, F M.
Analyst
Volume 135, 2010. Pages 712-719.

#222 - Characterization of Aziridinylbenzoquinone DNA Cross-links by liquid chromatography-infrared multiphoton dissociation mass spectrometry

Pierce, S., Guziec, L., Guziec, F., Brodbelt, J.S.
Chem. Res. Tox.
Volume 23, 2010. Pages 1097-1104.

#221 - Rapid and Selective Screening for Sulfhydryl Analytes in Plasma and Urine using Surface-Enhanced Transmission Mode Desorption Electrospray Ionization Mass Spectrometry

Chipuk, Joseph; Gelb, Michael; Brodbelt, Jennifer.
Anal Chem
Volume 82, 2010. Pages 4130-4139.

#220 - Rapid characterization of cross-links, mono-adducts, and non-covalent binding of psoralens to deoxyoligonucleotides by LC—UV/ESI-MS and IRMPD mass spectrometry

Smith, S.I., Brodbelt, J.S.
Analyst
Volume 135, 2010. Pages 943-952.

#219 - Increased Sequence Coverage of Thymine-rich Oligonucleotides by Infrared Multiphoton Dissociation Compared to Collision Induced Dissociation

Parr, C., Brodbelt, J.S.
J. Mass Spectrom.
Volume 45, 2010. Pages 1098-1103.

#218 - Infrared Multiphoton Dissociation of Small-Interfering RNA Anions and Cations

Gardner, MW., Li, N., Ellington, A.D., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 21, 2010. Pages 580-591.

#217 - Surface-Enhanced Transmission Mode Desorption Electrospray Ionization: Increasing the Specificity of Ambient Ionization Mass Spectrometric Analyses

Chipuk, J., Gelb, M., Brodbelt, J.S.
Anal. Chem.
Volume 82, 2010. Pages 16-18.

#216 - Asymmetric Charge Partitioning upon Dissociation of DNA Duplexes

Madsen, J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 21, 2010. Pages 1144-1150.

#215 - Reduction of Chemical Noise in Electrospray Ionization Mass Spectrometry by Supplemental IR Activation

Gardner, M.A., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 20, 2009. Pages 526-527.

#214 - Top-Down Protein Fragmentation by Infrared Multiphoton Dissociation in a Dual Pressure Linear Ion Trap

Madsen, J.A., Gardner, M.W., Smith, S.I, Ledvina, A.R., Coon, J.J., Schwartz, J.C., Stafford, G.C., Brodbelt, J.S.
Anal. Chem.
Volume 81, 2009. Pages 8677-8686.

#213 - Enhanced Electron Transfer Dissociation through Fixed Charge Derivatization of Cysteines

Vasicek, L., Brodbelt, J.S.
Anal. Chem.
Volume 81, 2009. Pages 7876-7884..

#212 - Infrared Multiphoton Dissociation of Peptide Cations in a Dual Quadrupole Linear Ion Trap Mass Spectrometer

Gardner, M.A., Ledvina, A.R.,Smith, S., Madsen, J., Schwartz, G.C., Stafford, G.C., Coon, J.J., Brodbelt, J.S.
Anal. Chem.
Volume 81, 2009. Pages 8109-8118.

#211 - Infrared Photoactivation reduces peptide folding and hydrogen atom migration following ETD tandem mass spectrometry

Ledvina, A.R., McAlister, G.C., Gardner, M.W., Smith, S.I, Madsen, J.A., Schwartz, J.C., Stafford, G.C., Syka, J.E.P, Brodbelt, J.S., Coon, J.J.
Angew Chem. Intl. Ed
Volume 48, 2009. Pages 1-4.

#210 - Examination of the effect of the annealing cation on higher order structures containing guanine or isoguanine repeats

Pierce, S.E., Wang, J., Jayawichramarajah, J., Hamilton, A.D., Brodbelt, J.S.
Chemistry: A European Journal.
Volume 15, 2009. Pages 11244-11255.

#209 - Interactions of Sulfur-Containing Acridine Ligands with DNA by ESI-MS

Smith, S., Guziec, F.S., Guziec, L., Brodbelt, J.S.
The Analyst
Volume 134, 2009. Pages 2058-2066.

#208 - rate-Determining Insertion of C=X Bonds in Rhodacyclopentadiences and Bronsted Acid Cocatalyzed Hydrogenolysis of Organorhodium Intermediates: ESI-MS, DFT and Synthetic Studies on the H–Mediated Coupling of Acetylene

Williams, V., Kong, J.R., Ko, B. J., Mantri, Y., Brodbelt, J.S., Baik, M.-H., Krische, M.J.
J. Am. Chem. Soc
Volume 131, 2009. Pages 16054-16062.

#207 - Ultraviolet Photodissociation Mass Spectrometry of Bis-aryl Hydrazone Conjugated Peptides

Gardner, M.W., Brodbelt, J.S.
Anal. Chem
Volume 81, 2009. Pages 4864-4872.

#206 - Electron Transfer Dissociation of Oligonucleotide Cations

Smith, S., Brodbelt, J.S.
Int. J. Mass Spectrom.
Volume 283, 2009. Pages 85-93.

#205 - Absorption, conjugation and efflux of the flavonoids, keampferol and galangin, using the intestinal CaCo-2/TC7 cell model

Barrington, R., Williamson, G., Bennett, R.N., Davis, B.D., Brodbelt, J.S., Kroon, P.A.
J. Functional Foods
Volume 1, 2009. Pages 74-87.

#204 - Evaluation of Binding Selectivities and Affinities of Platinum-Based Quadruplex Interactive Complexes by Electrospray Ionization Mass Spectrometry

Pierce, S.E., Kieltyka, R., Sleiman, H.F., Brodbelt, J.S.
Biopolymers
Volume 91, 2009. Pages 233-243.

#203 - Infrared Multiphoton Dissociation in Quadrupole Ion Traps

Brodbelt, J.S., Wilson, J.J.
Mass Spectrom. Rev.
Volume 28, 2009. Pages 390-424.

#202 - Simplifying Fragmentation Patterns of Multiply Charged Peptides by N-terminal Derivatization and Electron Transfer Collision Activated Dissociation

Madsen, J., Brodbelt, J.S.
Anal. Chem.
Volume 81, 2009. Pages 3645-3653.

#201 - The Influence of Material and Mesh Characteristics on Transmission Mode Desorption Electrospray Ionization

Chipuk, J.C., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 20, 2009. Pages 584-592.

#200 - Comparison of Infrared Multiphoton and Collision Induced Dissociation of Supercharged Peptides in Ion Traps

Madsen, J.A., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 20, 2009. Pages 349-358.

#199 - Improved Infrared Multiphoton Dissociation of Peptides through N-Terminal Phosphonite Derivatization

Vasicek, L.A., Wilson, J.J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 20, 2009. Pages 377-384.

#198 - Gas-Phase Hydrogen/Deuterium Exchange of Dinucleotides and 5’-Monophosphate Dinucleotides in a Quadrupole Ion Trap

Chipuk, J.C., Brodbelt, J.S.
Int. J. Mass Spectrom.
Volume 287, 2009. Pages 87-95.

#197 - Absorption, metabolism and excretion of flavanones from single portions of orange fruit and juice and effects of anthropometric variables and contraceptive pill use on flavanone excretion

Brett, G.M., Hollands, W., Needs, P.W., Teucher, B., Dainty, J., Bennett, R.N., Davis, B.D., Brodbelt, J.S., Kroon, P.A.
British Journal of Nutrition
Volume 101, 2009. Pages 664-675.

#196 - Ultraviolet Photodissociation at 355 nm of Fluorescently-Labeled Oligosaccharides

Wilson, J., Brodbelt, J.S.
Anal. Chem.
Volume 80, 2008. Pages 5186-5196.

#195 - Analysis of Flavonoids: Tandem Mass Spectrometry, Computational Methods, and NMR

March, R.E., Brodbelt, J.S.
J. Mass Spectrom.
Volume 43, 2008. Pages 1581-1617.

#194 - Transmission Mode Desorption Electrospray Ionization

Chipuk, J.E., Brodbelt, J.S.
J. Am. Soc Mass Spectrom.
Volume 19, 2008. Pages 1612-1620.

#193 - ESI-MS Characterization of a Pyrrole-Inosine Nucleoside that Selectively Targets Quadruplex DNA

Pierce, S., Sherman, C., Jayawickramarajah, J, Lawrence, C., Sessler, J, Brodbelt, J.
Analytical Chimica Acta.
Volume 627, 2008. Pages 129-135. (PMID 18790136).

#192 - An Investigation of the Homolytic Saccharide Cleavage of Deprotonated Flavonoid 3-O-Glycosides in a Quadrupole Ion Trap Mass Spectrometer

Davis, B.D., Brodbelt, J.S.
J. Mass Spectrom.
Volume 43, 2008. Pages 1045-1052.

#191 - Impact of Proline and Aspartic Acid Residues on the Dissociation of Intermolecularly Crosslinked Peptides

Gardner, M., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 19, 2008. Pages 344-357.

#190 - Regioselectivity of Human UDP-Glucuronsyltransferase 1A1 in the Synthesis of Flavonoid Glucuronides Determined by Metal Complexation and Tandem Mass Spectrometry

Davis, B.D., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 19, 2008. Pages 246-256.

#189 - Chromogenic Crosslinker for the Characterization of Protein Structure by Infrared Multiphoton Dissociation Mass Spectrometry

Gardner, M., Vasicek, L., Shabbir, S., Anslyn, E., Brodbelt, J.S.
Anal. Chem.
Volume 80, 2008. Pages 4807-4819.

#188 - Non-Covalent Complexation and Energy Transfer for Peptide Photodissociation in the Gas Phase

Wilson; J., Kirkovits; G.J., Sessler, J.L., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 19, 2008. Pages 257-260.

#187 - Sequencing and Characterization of Oligosaccharides using Infrared Multiphoton Dissociation and Boronic Acid Derivatization in a Quadrupole Ion Trap

Pikulski, M., Hargrove, A., Shabbir, S., Anslyn, E., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 18, 2007. Pages 2094- 2106.

#186 - MS/MS Simplification by 355 nm Ultraviolet Photodissociation of Chromophore-Derivatized Peptides in a Quadrupole Ion Trap

Wilson, J., Brodbelt, J.S.
Anal. Chem.
Volume 79, 2007. Pages 7883- 7892.

#185 - Isomeric differentiation of green tea catechins using gasphase hydrogen/deuterium exchange reactions

Niemeyer, E.D., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 18, 2007. Pages 1749- 1759.

#184 - X-Ray Crystallographic and Mass Spectrometric Probing of the Conformational and Ionophoric Properties of Stereoisomeric Hexatetrahydrofuranylhexane Segments

Hilmey, D.G., Davis, B.D., Gallucci, J.C., Brodbelt, J.S., Paquette, L.A.
J. Org. Chem.
Volume 72, 2007. Pages 9088-9101.

#183 - Synthesis and Unambiguous Structural Assignments to the Stereoisomers of Bis (2,2)- and Tris (2,2,2)-tetrahydrofurans. Conformational Features and Ionic Binding Capacities of these Gateway Polycyclic Networks

Adaligil, E., Davis, B.D., Hilmey, D.G., Shen, Y., Spruell, J.M., Brodbelt, J.S., Houk, K.N., Paquette, L.A.
J. Org. Chem.
Volume 72, 2007. Pages 6215-6223.

#182 - Probing Ligand Binding to Duplex DNA using KMnO4 Reactions and Electrospray Ionization Tandem Mass Spectrometry

Mazzitelli, C.L., Brodbelt, J.S.
Anal. Chem.
Volume 79, 2007. Pages 4636-4647. (PMID 17508717).

#181 - Evaluation of Metal-Mediated DNA Binding of Benzoxazole Ligands by Electrospray Ionization Mass Spectrometry

Mazzitelli, C.L., Rodriguez, M., Kerwin, S., Brodbelt J.S.
J. Am. Soc. Mass Spectrom.
Volume 19, 2007. Pages 209-218. (PMID 17583529).

#180 - Gas-Phase Stability of G-quadruplex DNA Determined by Electrospray Ionization Tandem Mass Spectrometry and Molecular Dynamics Simulations

Mazzitelli, C., Wang, J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 18, 2007. Pages 1760-1773. (PMID 17719795).

#179 - Evaluation of Relative DNA Binding Affinities of Anthrapyrazoles by Electrospray Ionization Mass Spectrometry

Smith, S., Guziec, L.J., Guziec, Jr., F.S., Hasinoff, B.B., Brodbelt, J.S.
J. Mass Spectrom.
Volume 42, 2007. Pages 681-688. (PMID 17405184).

#178 - Investigation of the Gas-Phase Hydrogen/Deuterium Exchange Behavior of Aromatic Dicarboxylic Acids in a Quadrupole Ion Trap

Chipuk, J., Brodbelt, J.S.
Int. J. Mass Spectrom.
Volume 267, 2007. Pages 98-108.

#177 - Infrared Multiphoton Dissociation of Duplex DNA/Drug Complexes in a Quadrupole Ion Trap

Wilson, J., Brodbelt, J.S.
Anal. Chem.
Volume 79, 2007. Pages 2067-2077. (PMID 17249688).

#176 - Tunable Transition Metal-Ligand Systems for Enhanced Elucidation of Flavonoid Diglycosides by Electrospray Ionization Mass Spectrometry

Pikulski, M., Aguilar, A., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 18, 2007. Pages 422-431.

#175 - Amplification of Infrared Multiphoton Dissociation Efficiency in a Quadruple Ion Trap by Using IR-Active Ligands

Pikulski, M., Wilson, J., Aguilar, A., Brodbelt, J.S.
Anal. Chem.
Volume 78, 2006. Pages 8512-8517.

#174 - Gas-phase Hydrogen/Deuterium Exchange of 5’ and 3’- Mononucleotides in a Quadrupole Ion Trap: Exploring the Role of Conformation and System Energy

Chipuk, J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 18, 2007. Pages 724-736.

#173 - Screening of Threading Bis-Intercalators Binding to Duplex DNA by Electrospray Ionization Tandem Mass Spectrometry

Mazzitelli, C.L., Chu, Y., Reczek, J.J., Iverson, B.L., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 18, 2007. Pages 311-321. (PMID 17098442).

#172 - Infrared Multiphoton Dissociation for Enhanced De Novo Sequence Interpretation of N-terminal Sulfonated Peptides in a Quadrupole Ion Trap

Wilson, J.J., Brodbelt, J.S.
Anal. Chem
Volume 78, 2006. Pages 6855-6862.

#171 - Structural Evaluation of the Adduct Between a 4-Aza-3-ene-1,6-diyne and DNA Using Electrospray Ionization Mass Spectrometry

Sherman, C.L., Pierce, S., Brodbelt, J.S., Tuesuwan, B., Kerwin, S.M.
J. Am. Soc. Mass Spectrom.
Volume 17, 2006. Pages 1342-1352. (PMID 16872840).

#170 - Investigation of Silver Binding to Polyamidoamine (PAMAM) Dendrimers by ESI Tandem Mass Spectrometry

Mazzitelli, C.L., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 17, 2006. Pages 676- 684.

#169 - Synthesis and Characterization of Insulin-Transferrin Conjugates

Kavimandan, N., Losi, E., Wilson, J.J., Brodbelt, J.S., Peppas, N.A.
Bioconjugate Chemistry
Volume 17, 2006. Pages 1376- 1384.

#168 - Evaluation of Binding of Perylene Diimide and Benzannulated Perylene Diimide Ligands to DNA by Electrospray Ionization Mass Spectrometry

Mazzitelli, C.L., Kern, J.T., Rodriguez, M., Brodbelt, J., Kerwin, S.
J. Am. Soc. Mass Spectrom.
Volume 17, 2006. Pages 593-604. (PMID 16503153).

#167 - Identification of Isomeric Flavonoid Glucuronides in Urine and Plasma by Metal Complexation and Liquid Chromatography/Tandem Mass Spectrometry

Davis, B.D., Needs, P., Kroon, P., Brodbelt, J.S.
J. Mass Spectrom.
Volume 41, 2006. Pages 911-920.

#166 - Influence of Initial Charge State on Fragmentation Patterns of Non-Covalent Drug/DNA Duplex Complexes

Keller, K.M., Zhang, J., Oehlers, L., Brodbelt, J.S.
J. Mass Spectrom.
Volume 49, 2005. Pages 1327-1337. (PMID 16220501).

#165 - Electrospray Ionization Mass Spectrometry of Nucleic Acid Aptamer/Small Molecule Complexes for Screening Aptamer Selectivity

Keller, K.M., Zhang, J., Breeden, M.M., Ellington, A.D., Brodbelt, J.S.
J. Mass Spectrom.
Volume 40, 2005. Pages 1362-1371. (PMID 16217837).

#164 - Investigating Bidentate and Tridentate Carbamoylmethylphosphine Oxide (CMPO) Ligand Interactions with Rare Earth Elements Using Electrospray Ionization Mass Spectrometry

Crowe, M., Kapoor, R., Cervantes-Lee, F., Párkányí, L., Schulte, L., Pannell, K.H., Brodbelt J.S.
Inorg. Chem.
Volume 44, 2005. Pages 6415-6424.

#163 - Rapid Adsorptive Separation of Citrus Polymethoxylated Flavones in Non-aqueous Conditions

Raman, G., Jayaprakasha, G.K., Cho, M., Brodbelt, J., Patil, B.S.
Separation and Purification Technology
Volume 45, 2005. Pages 147-152.

#162 - Electrospray Ionization Mass Spectrometric Detection of Self-Assembly of a Novel Crown Ether Complex Directed by PiStacking Interactions

Sherman, C., Brodbelt, J.S., Marchand, A.P., Poola, B.
J. Am. Soc. Mass Spectrom.
Volume 16, 2005. Pages 1162-1171.

#161 - Differentiation of Phosphorylated and Unphosphorylated Peptides by High Performance Liquid Chromatography/Electrospray Ionization/Infrared Multiphoton Dissociation in a Quadrupole Ion Trap

Crowe, M.C., Brodbelt, J.S.
Anal. Chem.
Volume 77, 2005. Pages 5726-5734.

#160 - Enantioselective reductive cyclization of 1,6-enynes via rhodium catalyzed asymmetric hydrogenation: C-C bond formation precedes hydrogen activation

Jang, H.-Y., Hughes, F.W., Gong, H., Zhang, J., Brodbelt, J.S., Krische, M.J.
J. Am. Chem. Soc.
Volume 127, 2005. Pages 6174-6175.

#159 - Electrochemical, Spectroscopic and Mass Spectrometric Studies of the Interaction of Silver Species with Polyamidoamine Dendrimers

Fan, F.F., Mazzitelli, C., Brodbelt, J.S., Bard, A.J.
Anal. Chem.
Volume 77, 2005. Pages 4413-4422.

#158 - LC-MS n Methods for Saccharide Characterization of Monoglycosyl Flavonoids Using Post-Column Manganese Complexation

Davis, B., Brodbelt, J.S.
Anal. Chem.
Volume 77, 2005. Pages 1883-1890.

#157 - A Partitioning Model for Competitive Host-Guest Complexation in Electrospray Ionization Mass Spectrometry

Sherman, C.L., Brodbelt, J.S.
Anal. Chem.
Volume 77, 2005. Pages 2512- 2523.

#156 - Duplex and Quadruplex DNA Binding and Photocleavage by Trioxatriangulenium Ion

Pothukuchy, A., Mazzitelli, C., Salazar, M., Brodbelt, J.S., Kerwin, S.M.
Biochemistry
Volume 44, 2005. Pages 2163-2172. (PMID 15697242).

#155 - Silver Complexation and Tandem Mass Spectrometry for Differentiation of Isomeric Flavonoid Diglycosides

Zhang J., Brodbelt, J.S.
Anal. Chem.
Volume 77, 2005. Pages 1761-1770.

#154 - Characterization of Flavonoids by Aluminum Complexation and Collisional Activated Dissociation

Zhang, J., Wang, J., Brodbelt, J.S.
J. Mass Spectrom.
Volume 40, 2005. Pages 350-363.

#153 - Evaluation of Metal Cation Complexation Properties of Cage-annulated Macrocyclic Hosts via Electrospray Ionization Mass Spectrometry (ESI-MS)

Marchand, A.P., Brodbelt, J.S., Mlinaric-Majerski, K.
Kem. Ind
Volume 54, 2005. Pages 89-98.

#152 - Charge State-Dependent Fragmentation of Oligonucleotide/Metal Complexes

Keller K.M., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 16, 2005. Pages 28-37.

#151 - Is Potential Coordination of Alkali Metal Ions to Sterodefined Polyoxygenated Cyclohexanes an Adequate Driving Force for Fostering the Adoption of Axial Conformers?

Paquette, L.A., Selveraj, P.R., Keller, K., Brodbelt, J.S.
Tetrahedron
Volume 61, 2005. Pages 231-240.

#150 - Threshold Dissociation and Molecular Modeling of Transition Metal Complexes of Flavonoids

Zhang, J., Wang, J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 16, 2005. Pages 139-151.

#149 - Isolation and Purification of Closely Related Citrus Limonoid Glucosides by Flash Chromatography

Raman, G., Cho, M., Brodbelt, J.S., Patil, B.S.
Phytochemical Analysis
Volume 16, 2005. Pages 155-160.