#288 - Evolving tRNASec for efficient canonical incorporation of selenocysteine
Thyer, R., Robotham, S.A., Brodbelt, J.S., Ellington, A.
J. Am. Chem. Soc.
Volume 137(1), 2014. Pages 46-49.
#287 - Improvement of Shotgun Proteomics in the Negative Mode by Carbamylation of Peptides and Ultraviolet Photodissociation Mass Spectrometry
Greer, S.M., Cannon, J.R, Brodbelt, J.S.
Anal. Chem.
Volume 86, 2014. Pages 12285-12290.
#286 - Characterization of Pseudomonas aeruginosa LpxT reveals dual positional lipid A kinase activity and coordinated control of outer membrane modification
Nowicki, E., O’Brien, J.P., Brodbelt, J.S., Trent, M.S.
Mol. Micro
Volume 94(3), 2014. Pages 728-741.
#285 - Covalent Inhibition of New Delhi Metallo-Beta-Lactamase-1 (NDM-1) by Cefaclor
Thomas, P.W., Cammarata, M., Brodbelt, J.S., Fast, W.
ChemBioChem
Volume 15(17), 2014. Pages 2541-2548.
#284 - Antimicrobial Peptide Resistance of Vibrio cholerae Results From LPS Modification Pathway Related to Non-ribosomal Peptide Synthetases
Henderson, J., Fage, C.D., Cannon, J.R., Brodbelt, J.S., Keatinge-Clay, A.T., Trent, M.S.
ACS Chemical Biology
Volume 9(10), 2014. Pages 2382-2392.
#283 - Hybridizing Ultraviolet Photodissociation with Electron Transfer Dissociation for Intact Protein Characterization
Cannon, J.R., Holden, D.D., Brodbelt, J.S.
Anal. Chem
Volume 86, 2014. Pages 10970-10977.
#282 - The Molecular Mechanism of Eukaryotic Elongation Factor 2 Kinase Activation
Tavares, C., O’Brien, J., Brodbelt, J.S., Dalby, K.
J. Biol Chem.
Volume 289(34), 2014. Pages 23901-23916.
#281 - Elucidation of Native Protein Complexes Using Ultraviolet Photodissociation Mass Spectrometry
O’Brien, J.P., Li, W., Zhang, Y., Brodbelt, J.S.
J. Am. Chem. Soc.
Volume 136, 2014. Pages 12920-12928.
#280 - The First Pilot Project for the Consortium for Top Down Proteomics: A Status Report
Dang, X., Scotcher, J., Shaw, J., Ntai, I., Thomas, P.M., Fellers, R.X., Early, B.X., LeDuc, R.X., Wu, S., Zhang, Z., Tolic, N., Wolff, J.J., Easterling, M., Borchers, C.H., Brodbelt, J.S., Agar, J.N., Kelleher, N.L., Pasa-Tolic, L., Young., N.L.
Proteomics
Volume 14(10), 2014. Pages 1130-1140.
#279 - Top-Down Ultraviolet Photodissociation for the structural elucidation of intact lipopolysaccharides
O’Brien, J.P.; Needham, B.; Brown D.; Trent, M.S.; Brodbelt, J.S.
Chemical Science
Volume 5, 2014. Pages 4291-4301.
#278 - Streamlining Bottom-Up Protein Identification Based on Selective Ultraviolet Photodissociation (UVPD) of Chromophore-Tagged Histidine- and Tyrosine-Containing Peptides.
Aponte, J.R.; Vasicek, L.; Swaminathan, J.; Xu ,H.; Koag, M.C.; Lee, S.; Brodbelt, J.S.
Analytical Chemistry
Volume 86, 2014. Pages 6237-6244.
#277 - Mechanically modulating the photophysical properties of fluorescent protein biocomposites for ratio- and intensiometric sensors.
Brantley, J.N.; Bailey, C.B.; Cannon, J.R.; Clark, K.A.; Vanden Bout, D.A.; Brodbelt, J.S.; Keatinge-Clay, A.T.; Bielawski, C.W.
Angew Chem Int Ed Engl
Volume 53, 2014. Pages 5088-5092.
#276 - Direct Identification of Tyrosine Sulfation by using Ultraviolet Photodissociation Mass Spectrometry.
Robinson, M.R.; Moore, K.L.; Brodbelt, J.S.
J Am Soc Mass Spectrom.
Volume 25(8), 2014. Pages 1461-1471.
#275 - Photodissociation mass spectrometry: new tools for characterization of biological molecules.
Brodbelt, J.S.
Chem. Soc. Rev
Volume 43, 2014. Pages 2757-2783.
#274 - Probing the Unfolding of Myoglobin and Domain C of PARP-1 with Covalent Labeling and Top-Down 193 nm Ultraviolet Photodissociation Mass Spectrometry
Cammarata, M.; Lin, K.; Pruet, J.M.; Liu, H.; Brodbelt, J.S.
Anal Chem
Volume 86, 2014. Pages 2534-2542.
#273 - Characterization of Green Fluorescent Proteins by 193 nm Ultraviolet Photodissociation Mass Spectrometry
Cannon, J.; Klue, C.; Ellington, A.; Brodbelt, J.S.
Proteomics
Volume 14(10), 2014. Pages 1165-1173.
#272 - 193 nm Ultraviolet Photodissociation Mass Spectrometry for the Structural Elucidation of Lipid A Compounds in Complex Mixtures
O’Brien JP, Needham BD, Henderson JC, Nowicki EM, Trent MS, and Brodbelt JS
Anal. Chem
Volume 86, 2014. Pages 2138-2145.
#271 - Ultraviolet Photodissociation for Characterization of Whole Proteins on a Chromatographic Timescale
Cannon JR, Cammarata MB, Robotham SA, Cotham VC, Shaw JB, Fellers RT, Early BP, Thomas PM, Kelleher NL, and Brodbelt JS
Anal Chem
Volume 86, 2014. Pages 2185-2192.
#270 - Identification of a broad family of lipid A late acyltransferases with non-canonical substrate specificity.
Rubin EJ, O'Brien JP, Ivanov PL, Brodbelt JS, Trent MS
Mol. Micro
Volume 91, 2014. Pages 887-899.
#269 - Isolation and Chemical Characterization of Lipid A from Gram-negative Bacteria.
Henderson J.C., O'Brien J.P., Brodbelt J.S., Trent M.S.
J Vis Exp.
Volume 79, 2013. Pages e50623, doi:10.3791/50623.
#268 - Evaluating the Conformation and Binding Interface of Cap Binding Proteins and Complexes via Ultraviolet Photodissociation Mass Spectrometry
O’Brien, J.P., Mayberry, L.K., Murphy, P.A., Browning, K.S. and Brodbelt, J.S.
Journal of Proteome Research
Volume 12, 2013. Pages 5867–5877.
#267 - Differentiation and Distributions of DNA/Cisplatin Crosslinks by Infrared Multiphoton Dissociation Mass Spectrometry
Xu, Z., Brodbelt, J.S.,
J. Am. Soc. Mass Spectrom
Volume 25, 2014. Pages 71-79..
#266 - Structural Characterization of Gangliosides and Glycolipids via Ultraviolet Photodissociation Mass Spectrometry
O’Brien, J.P., Brodbelt, J.S.
Anal. Chem.
Volume 85, 2013. Pages 10399–10407.
#265 - De Novo Sequencing of Peptides Using Selective 351 nm Ultraviolet Photodissociation Mass Spectrometry
Robotham, S.A., Kluwe, C., Ellington, A., Brodbelt, J.S.
Anal. Chem.
Volume 85, 2013. Pages 9832–9838.
#264 - Concurrent Automated Sequencing of the Glycan and Peptide Portions of O-Linked Glycopeptide Anions
Madsen, J.A., Ko, B.Y.., Xu, H., Horton, A.P., Iwashkiw, J.A., Shaw, J.B., Feldman, M.F., Brodbelt, J.S.
Anal. Chem
Volume 85, 2013. Pages 9253–9261.
#263 - Novel modifications on C-terminal Domain of RNA Polymerase II can modulate the phosphatase activity of Ssu72
Luo, Y., Yogesha, S.D., Cannon, J.R., Yan, W., Brodbelt, J.S., Zhang, Y.
ACS Chemical Biology
Volume 8, 2013. Pages 2042–2052.
#262 - Extending the isotopically resolved mass range of Orbitrap mass spectrometers
Shaw, J.B., Brodbelt, J.S.
Anal. Chem.
Volume 85, 2013. Pages 8313–8318.
#261 - Directed evolution of genetic circuits by compartmentalized partnered replication (CPR)
Ellefson, J.W., Meyer, A.J., Hughes, R.A., Cannon, J., Brodbelt, J.S., Ellington, A.D.
accepted to Nature Biotechnology
2013.
#260 - Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation
Shaw, J.B., Li, W., Holden, D.D., Zhang, Y., Griep-Raming, J., Fellers, R.T., Early, B.P., Thomas, P.M., Kelleher, N.L., Brodbelt, J.S.
J. Am. Chem. Soc.
Volume 135, 2013. Pages 12646–12651.
#259 - Chromogenic Chemical Probe for Protein Structural Characterization via Ultraviolet Photodissociation Mass Spectrometry
O’Brien, J.P., Pruet, J., Brodbelt, J.S.
Anal. Chem.
Volume 85, 2013. Pages 7391–7397.
#258 - Regiospecificity of Human UDP-glucuronosyltransferase Isoforms in Chalcone and Flavanone Glucuronidation Determined by Metal Complexation and Tandem Mass Spectrometry
Niemeyer, E., Brodbelt, J.S.
J. Nat. Products
Volume 76, 2013. Pages 1121-1132.
#257 - Selective 351 nm Photodissociation of Cysteine-Containing Peptides for Improved Sequencing of Antigen-Binding Regions of IgG Fragments in Bottom-Up LC-MS/MS Workflows
Cotham, V.C., Wine, Y., Brodbelt, J.S.
Anal Chem
Volume 85, 2013. Pages 5577-5585.
#256 - Activated negative electron transfer dissociation of multiply charged peptide anions
Shaw, J.B., Kaplan, D.A., Brodbelt, J.S.
Anal. Chem.
Volume 85, 2013. Pages 4721-4728.
#255 - An altered zinc-binding site confers resistance to a covalent inactivator of New Dehli metallo-beta-lactamase-1 (NDM-1) discovered by high-throughput screening
Thomas, P.W., Spicer, T., Cammarata, M., Brodbelt, J.S., Hodder, P., Fast, W.
Biorg. Med. Chem.
Volume 21, 2013. Pages 3138-3146.
#254 - Tandem Mass Spectrometry for Characterization of Covalent Adducts of DNA with Anti-cancer Therapeutics
Silvestri, C., Brodbelt, J.S.
Mass Spectrom. Rev.
Volume 32, 2013. Pages 247-266.
#253 - The outer membrane of gram-negative bacteria: lipid A isolation and characterization.
Hankins, J.V., Madsen, J.A.,Needham, B.D., Brodbelt, J.S., Trent, M.S.
Methods Mol. Bio.
Volume 966, 2013. Pages 239-258.
#252 - Flavone Glucuronide Isomers Identified by Metal Complexation and Tandem Mass Spectrometry: Regioselectivity of UDP-Glucuronosyltransferase Isozymes in the Biotransformation of Flavones
Robotham, S.A., Brodbelt, J.S.
J. Ag. Food Chem.
Volume 61, 2013. Pages 1457-1463.
#251 - EptC of Campylobacter jejuni mediates phenotypes involved in host interactions and virulence.
Cullen, T.W., O’Brien, J.P., Hendrixson, D.R., Giles, D.K., Hobb, R.I., Thompson, S.A., Brodbelt, J.S., Trent, M.S.
Infection and Immunity
Volume 81, 2013. Pages 430-440.
#250 - Comparison of MS/MS Methods for Characterization of DNA/cis-platin Adducts
Xu, Z., Shaw, J.B., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom
Volume 24, 2012. Pages 265-272.
#249 - Tyrosine sulfation in gram-negative bacterium
Han, S-W., Lee, S-W., Bahar, O., Schwessinger, B., Robinson, MR., Shaw, J.B., Madsen, J.A., Brodbelt, J.S., Ronald, P.A.
Nature Commun.
Volume 3:1153, 2012. Pages doi: 10.1038/ncomms2157.
#248 - Tyrosine Deprotonation Yields Abundant and Selective Back-bone Cleavage in Peptide Anions upon Negative Electron transfer Dissociation and Ultraviolet Photodissociation
Shaw, J., Ledvina, A., Zhang, X., Julian, R.R., Brodbelt, J.S.
J. Am. Chem. Soc.
Volume 134, 2012. Pages 15624-15627.
#247 - Enhanced Electron Transfer Dissociation of Peptides Modified at C-terminus with Fixed Charges
Ko, B.J., Brodbelt, J.S
J. Am. Soc. Mass Spectrom
Volume 23, 2012. Pages 1991-2000.
#246 - Systematic Comparison of Ultraviolet Photodissociation and Electron Transfer Dissociation for Peptide Anion Characterization
Shaw, J., Madsen, J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom
Volume 23, 2012. Pages 1707-1715.
#245 - Amino acid addition to the bacterial surface confers polymyxin B resistance in V. cholerae
Hankins, J.V., Madsen, J.A., Giles, D.K., Brodbelt, J.S., Trent, M.S.
Proc. Nat. Acad. Sciences
Volume 109 (22), 2012. Pages 8722-8727.
#244 - 193 nm ultraviolet photodissociation of imidazolinylated lys-N peptides for de novo sequencing
Robinson, M.R., Madsen, J.A., Brodbelt, J.S.
Anal. Chem.
Volume 84, 2012. Pages 2433-2439.
#243 - Mapping and Analysis of the Autophosphorylation Sites in Recombinant Human Elongation Factor 2 Kinase (eEF-2K)
Tavares, C.D.J., O'Brien, J.P., Abramczyk, O., Devkota, A.K, Shores, K.S., Ferguson, S.B., Kaoud, T.S., Warthaka, M., Marshall, K.D., Keller, K.M., Zhang, Y., Brodbelt, J.S., Dalby, K.N.
Biochemistry
Volume 50, 2012. Pages 2232-2245.
#242 - Characterization of a unique modification of the flagellar rod protein FlgG by the Campylobacter jejuni lipid A phosphoethanolamine transferase
Cullen, T.W., Madsen, J.A., Ivanov, P.L., Brodbelt, J.S., Trent, M.S.
J. Biol. Chem
Volume 287, 2012. Pages 3326-3336.
#241 - Charge-site Dependent Dissociation of Hydrogen-Rich Radical Peptide Cations upon Vacuum UV Photoexcitation
Madsen, J.A., Cheng, R.R., Kaoud, T.S., Dalby, K.N., Makarov,D.E., Brodbelt, J.S.
accepted Chemistry: Eur. J.
Volume 18, 2012. Pages 5374-5383.
#240 - Mapping Protein Surface Accessiblity via an Electron Transfer Dissociation Selectively Cleavable Hydrozone Probe
Vasicek, L., O'Brien, J.P., Browning, K.S., Tao, Z., Liu, H.W., Brodbelt, J.S.
accepted to Mol. Cellular Proteomics
2012.
#239 - Regioselectivity of Human UDP-Glucuronosyltransferase Isozymes in Flavonoid Biotransformation by Metal Complexation and Tandem Mass Spectrometry
Robotham, S.A., Brodbelt, J.S.
Biochemical Pharmacology
Volume 82, 2011. Pages 1764-1770.
#238 - 193 nm Ultraviolet Photodissociation of Deprotonated Sialylated Oligosaccharides
Ko, B.J., Brodbelt, J.S.
Anal. Chem.
Volume 83, 2011. Pages 8192-8200.
#237 - Analysis of protein digests by transmission-model desorption electrospray ionization mass spectrometry with ultraviolet photodissociation
Shaw, J.B., Brodbelt, J.S.
Int. J. Mass Spectrom.
Volume 308, 2011. Pages 203-208.
#236 - Elucidation of a novel Vibrio Cholera lipid A secondary hydroxyl-acyltransferase and its roles in pathogenesis
Hankins, J.V., Madsen, J.A., Giles, D.K., Childers, B.M., Klose, K.E., Brodbelt, J.S., Trent, M.S.
Mol. Micro.
Volume 81, 2011. Pages 1313-1329.
#235 - Ultraviolet Photodissociation of Chromophore-labeled Oligosaccharides via Reductive Amination and Hydrazide Conjugation
Ko, B.J., Brodbelt, J.S.
J. Mass Spectrom.
Volume 46, 2011. Pages 359-366.
#234 - Shedding Light on the Frontier of Phodissociation
Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 22, 2011. Pages 197-206.
#233 - IR and UV Photodissociation as Analytical Tools for Characterizing Lipid A Structures
Madsen, J.A., Cullen, T.W., Trent, M.S., Brodbelt, J.S.
Anal. Chem.
Volume 83, 2011. Pages 5107-5113.
#232 - Implementation of Photodissociation on an Orbitrap mass Spectrometer
Vasicek, L.A., Ledvina, A.R., Shaw, J., Griep-Raming, J., Westphall, M.S., Coon, J.J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 2011, 22. Pages 1105-1108.
#231 - Ultraviolet Photodissociation of Carboxylate-Derivatized Peptides in a Quadrupole Ion Trap
Ko, B.J., Brodbelt, J.S.
J. Am. Soc. Mass Spectrom.
Volume 22, 2011. Pages 49-56.
#230 - 193 nm Photodissociation of Singly and Multiply Charged Peptide Anions for Acidic Proteome Characterization
Madsen, J., Kaoud, T., Dalby, K., Brodbelt, J.S.
Proteomics
Volume 11, 2011. Pages 1329-1334.
#229 - Hybrid Activation Methods for Elucidating Nucleic Acid Modifications
Smith, S.I., Brodbelt, J.S.
Anal. Chem
Volume 83, 2011. Pages 303-310.