Park, A., Ghezzi, A., Wijesekera, T. P., & Atkinson, N. S. (2017). Genetics and genomics of alcohol responses in drosophila. Neuropharmacology.

Ghezzi, A., Li, X., Lew, L. K., Wijesekera, T. P., & Atkinson, N. S. (2017). Alcohol-Induced Neuroadaptation Is Orchestrated by the Histone Acetyltransferase CBP. Frontiers in molecular neuroscience10.

Ghezzi A, Zomeno M, Pietrzykowski AZ, Atkinson NS.(2016) Immediate-early alcohol-responsive miRNA expression in Drosophila. J Neurogenet. Nov 15:1-10. [Epub ahead of print] PMID: 27845601

Atkinson NS.(2016) How the Ganetzky lab drove me to alcohol. J Neurogenet. Sep 1:1-4. [Epub ahead of print]  PMID: 27584572

Troutwine BR, Ghezzi A, Pietrzykowski AZ, Atkinson NS. (2016) Alcohol resistance in Drosophila is modulated by the Toll innate immune pathway. Genes Brain Behav. 2016 Apr;15(4):382-94. PMID: 26916032

Krishnan HR, Li X, Ghezzi A, Atkinson NS. (2016) A DNA element in the slo gene modulates ethanol tolerance. Alcohol. 2016 Mar;51:37-42. PMID: 26992698

Li X, Ghezzi A, Krishnan HR, Pohl JB, Bohm AY, Atkinson NS. (2015) A histone modification identifies a DNA element controlling slo BK channel gene expression in muscle.  J Neurogenet. 29:124-34 PMID: 25967280

Rothenfluh A, Troutwine BR, Ghezzi A, Atkinson NS (2014) The Genetics of Alcohol Responses of Invertebrate Model Systems. In: Neurobiology of Alcohol Dependence (Noronha ABC, Cui C, Harris RA, Crabbe JC, eds), Elsevier.

Ghezzi, A., H.R. Krishnan and N.S. Atkinson. 2014. Susceptibility to ethanol withdrawal seizures is produced by BK channel gene expression. Addiction Biology 2014 May;19(3):332-337. PMID: 22734584


Ghezzi, A, Krishnan, HR, Lew, L, Pardo, FJr, Ong, DS, and Atkinson, NS (2013). Alcohol-induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance. PLoS Genetics 9:e1003986. PMID: 24348266

Li, X, Ghezzi, A, Pohl, JB, Bohm, AY, Krishnan, HR, Atkinson, NS (2013) A DNA element regulates drug tolerance and withdrawal. PLoS One, 8:e75549

Robinson, B.G. and N.S. Atkinson. 2013. Is Alcoholism Learned? Insights from the Fruit Fly. Current Opinion in Neurobiology pii: S0959-4388(13)00032-9. doi: 10.1016/j.conb.2013.01.016. [Epub ahead of print]


Pohl, JB, Ghezzi, A, Lew, L, Robles, RB, Cormack, L, and Atkinson, NS (2013). Circadian genes differentially affect tolerance to ethanol in Drosophila. Alcohol Clin Exp Res doi: 10.1111/acer.12173.


Robinson, BG, Khurana, S, and Atkinson, NS (2013). Drosophila larvae as a model to study physiological alcohol dependence. Communicative and Integrative Biology 6:e23501. PMID: 23750304 PMCID: PMC3609852


Ghezzi, A., Y.M. Al-Hasan, H.R. Krishnan, Y. Wang and N.S. Atkinson. 2013. Functional mapping of the neuronal substrates for drug tolerance in Drosophila. Behav Genet 43: 227-240.


Robinson, B.G., S. Khurana, A. Kuperman and N.S. Atkinson. 2012. Neural Adaptation Leads to Cognitive Ethanol Dependence. Current Biology 22: 2338-2341.


Pohl, J.B., B.A. Baldwin, B.L. Dinh, P. Rahman, D. Smerek, F.J.r. Prado, N. Sherazee and N.S. Atkinson. 2012. Ethanol Preference in Drosophila melanogaster is Driven by Its Caloric Value. Alcohol Clin Exp Res 36: 1903-1912.


Khurana, S, Robinson, BG, Wang, Z, Shropshire, WC, Zhong, AC, Garcia, LE, Corpuz, J, Chow, J, Hatch, MM, Precise, EF, Cady, A, Godinez, RM, Pulpanyawong, T, Nguyen, AT, Li, WK, Seiter, M, Jahanian, K, Sun, JC, Shah, R, Rajani, S, Chen, WY, Ray, S, Ryazanova, NV, Wakou, D, Prabhu, RK, and Atkinson, NS (2012). Olfactory Conditioning in the Third Instar Larvae of Drosophila melanogaster Using Heat Shock Reinforcement. Behav Genet 42:151-161. PMID: 21833772


Robinson, B.G., S. Khurana, J.B. Pohl, W.K. Li, A. Ghezzi, A.M. Cady, K. Najjar, M.M. Hatch, R.R. Shah, A. Bhat, O. Hariri, K.B. Haroun, M.C. Young, K. Fife, J. Hooten, T. Tran, D. Goan, F. Desai, F. Husain, R.M. Godinez, J.C. Sun, J. Corpuz, J. Moran, A.C. Zhong, W.Y. Chen and N.S. Atkinson. 2012. A low concentration of ethanol impairs learning but not motor and sensory behavior in Drosophila larvae. PLoS One 7: e37394.


Krishnan HR, Al-Hasan YM, Pohl JB, Ghezzi A, Atkinson NS (2012) A role for dynamin in triggering ethanol tolerance. Alcohol Clin Exp Res 36: 24-34.


Al-Hasan YM, Krishnan HR, Ghezzi A, Prado FJr, Robles RB et al. (2011) Tolerance to anesthesia depends on synaptic proteins. Behav Genet 41: 734-745.


Khurana S, Robinson BG, Wang Z, Shropshire WC, Zhong AC et al. (2011) Olfactory Conditioning in the Third Instar Larvae of Drosophila melanogaster Using Heat Shock Reinforcement. Behav Genet 42: 151-161..


Ghezzi A, Atkinson NS (2011) Homeostatic control of neural activity: a Drosophila model for drug tolerance and dependence. Int Rev Neurobiol 99: 23-50.


Khurana S, Li WK, Atkinson NS (2010) Image enhancement for tracking the translucent larvae of Drosophila melanogaster. PLoS One 5: e15259.


Ghezzi, A, Pohl, JB, Wang, Y, Atkinson, NS (2010) BK Channels Play a Counteradaptive Role in Drug Tolerance and Dependence. Proc Natl Acad Sci U S A, 107:16360–16365


Atkinson, NS (2009) Tolerance in Drosophila. J Neurogenet, 23:293–302.


Wang, Y, Ghezzi, A, Yin, JC, Atkinson, NS (2009) CREB regulation of BK channel gene expression underlies rapid drug tolerance. Genes Brain Behav, 8:369–376.


Wang, Y, Krishnan, HR, Ghezzi, A, Yin, JC, Atkinson, NS (2007) Drug-Induced Epigenetic Changes Produce Drug Tolerance. PLoS Biol, 5:e265


Atkinson, NS, A, G, Wang, Y (2006) Regulación de un canal de K+ activado por Ca2+ tipo BK es la razón fundamental de la tolerancia de solventes organicos y etanol en el modelo de la Drosophila. Anuario de Investigación en Adicciones, 7:4–9.


Fernandez Mde, L, Chu, J, Villella, A, Atkinson, N, Kay, SA, Ceriani, MF (2007) Impaired clock output by altered connectivity in the circadian network. Proc Natl Acad Sci U S A, 104:5650–5655


Ramazani, RB, Atkinson, NS (2006) Computer automated quantification of movement in Drosophila melanogaster. Journal of Neuroscience Methods, 162:171–179.


Link to the software described in Ramazani et al 2006.


Yu, JY, Updadyaya, A, Atkinson, N (2006) Tissue-specific alternative splicing of BK channel transcripts in Drosophila. Genes, Brain & Behavior, 5:329–339.


Cowmeadow, RB, Krishnan, HR, Ghezzi, A, Al'hasan, Y, Wang, YZ, Atkinson, NS (2006) Ethanol Tolerance Caused by slowpoke Induction in Drosophila. Alcohol Clin Exp Res, 30:745–753.


Cowmeadow, RB, Krishnan, HR, Ghezzi, A, Al'hasan, Y, Wang, YZ, Atkinson, NS (2006) Ethanol Tolerance Caused by slowpoke Induction in Drosophila. Alcohol Clin Exp Res, 30:745–753.


Ghezzi, A, Al-Hasan, YM, Larios, LE, Bohm, RA, Atkinson, NS (2004) slo K+ channel gene regulation mediates rapid drug tolerance. Proc Natl Acad Sci U S A, 101:17276–17281.


Lopreato, GF, Lu, Y, Southwell, A, Atkinson, NS, Hillis, DM, Wilcox, TP, Zakon, HH (2001) Evolution and divergence of sodium channel genes in vertebrates. Proc Natl Acad Sci U S A, 98:7588–7592.


Atkinson, NS, Brenner, R, Chang, W-, Wilbur, JL, Larimer, JL, Yu, J (2000) Molecular separation of two behavioral phenotypes by a mutation affecting the promoters of a Ca-activated K channel. J. Neurosci., 20:2988–2993.


Bohm, RA, Wang, B, Brenner, R, Atkinson, N (2000) Transcriptional control of Ca-activated K channel expression: identification of a second, evolutionarily-conserved, neuronal promoter. J. Exp. Biol., 203:693–704. 


Brenner, R, Yu, JY, Srinivasan, K, Brewer, L, Larimer, JL, Wilbur, JL, Atkinson, NS (2000) Complementation of physiological and behavioral defects by a slowpoke Ca2+-activated K+ channel transgene. J. Neurochem., 75:1310–1319.


Chang, W-, Bohm, RA, Strauss, JC, Kwan, T, Thomas, T, Cowmeadow, RB, Atkinson, NS (2000) Muscle-specific transcriptional regulation of the slowpoke Ca2+- activated K+ channel gene. J. Biol. Chem., 275:3991–3998.


Atkinson, NS, Brenner, R, Bohm, RA, Yu, JY, Wilbur, JL (1998) Neuronal Mechanisms for Generating Locomoter Activity: Behavioral and electrophysiological analysis of Ca-activated K- channel transgenes in Drosophila. Annals of the New York Academy of Sciences, 860:296–305.


Chang, W- (1998) Identification of transcriptional regulatory elements in muscle promoter of Ca++-activated potassium channel, slowpoke, in Drosophila. Thesis.


Brenner, R, Atkinson, NS (1997) Calcium-activated potassium channel gene expression in the midgut of Drosophila. Comp. Biochem. Physiol. B. Biochem. Mol. Biol., 118:411–420.


Thomas, T, Wang, B, Brenner, R, Atkinson, NS (1997) Novel embryonic regulation of Ca(2+)-activated K+ channel expression in Drosophila. Invert. Neurosci., 2:283–291.


Brenner, R, Atkinson, N (1996) Developmental and Eye-specific transcriptional control elements in an intronic region of a Ca2+-activated K+ channel gene. Dev. Biol., 177:536–543.


Brenner, R, Thomas, TO, Becker, MN, Atkinson, NS (1996) Tissue-specific expression of a Ca2+-activated K+ channel is controlled by multiple upstream regulatory elements. J. Neurosci., 16:1827–1835.


Becker, MN, Brenner, R, Atkinson, NS (1995) Tissue-specific expression of a Drosophila Calcium-activated Potassium channel. J. Neurosci., 15:6250–6259.


Ganetzky, B, Warmke, J, Robertson, G, Atkinson, N, Drysdale, R (1994) Genetic and molecular analysis of potassium channels in Drosophila. Insect Neurochemistry and Neurophysiology 1993:9–22.


Atkinson, NS, Robertson, GA, Ganetzky, B (1991) A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science, 253:551–555.