Facility Publications and Presentations
Publications
- Combining Chemistry and Engineering for Hepatocellular Carcinoma: Nano-Scale and Smaller Therapies. Stolley DL, Crouch AC, Ozkan A, Seeley EH, Whitley EM, Rylander MN, Cressman ENK. Pharmaceutics. 2020, 12, 1243.
- Perspective on Mass Spectrometry Imaging for In Situ Visualization of Chemotherapeutics Delivered via Nanoparticle Encapsulation. Seeley EH. Clin Chem. 2021, 67, 1172-1174.
- Reduced Hemoglobin Signal and Improved Detection of Endogenous Proteins in Blood-Rich Tissues for MALDI Mass Spectrometry Imaging. Lin M, Eberlin LS, Seeley EH. J Am Soc Mass Spectrom. 2022, 33, 296-303.
- Are Mass Spectrometry Imaging-Based Diagnostics Becoming Reality? Seeley EH. Proteomics. Clin Appl. 2022, Apr 8:e2200017. doi: 10.1002/prca.202200017.
- Lactate is an Epigenetic Metabolite that Drives Survival in Model Systems of Glioblastoma. Torrini C, Nguyen TTT, Shu C, Mela A, Humala N, Mahajan A, Seeley EH, Zhang G, Westhoff M-A, Karpel-Massler G, Bruce JN, Canoll P, Sieflein MD. Mol Cell. 2022, 82(16), 3061-3076.
- In Situ Imaging of O-Linked B-N-Acetylglucoseamine Using On-Tissue Hydrolysis and MALDI Mass Spectrometry. Escobar EE, Seeley EH, Serrano-Negron JE, Vocadlo DJ, Brodbelt JS. Cancers. 2023, 15(4), 1224-1239.
- Spatially Resolved Metabolites in Stable and Unstable Human Atherosclerotic Plaques Indentified by Mass Spectrometry Imaging. Seeley EH, Liu Z, Yuan S, Stroope C, Cockerham E, Rashdan NA, Delgadillo LF, Finney AC, Kumar D, Das S, Razani B, Liu W, Traylor J, Orr AW, Rom O, Pattillo CB, Yurdagul A Jr. ArteriosclerThromb Vasc Biol. 2023, 43(9), 1626-1635.
- TNFR1 Signaling Converging on FGF14 Controls Neuronal Hyperactivity and Sickness Behavior in Experimental Cerebral Malaria. Dvorak NM, Domingo ND, Tapia CM, Wadsworth PA, Marosi M, Avchalumov Y, Fongsaran C, Koff L, Di Re J, Sampson CM, Baumgartner TJ, Wang P, Villarreal PP, Solomon OD, Stutz SJ, Aditi, Porter J, Gbedande K, Prideaux B, Green TA, Seeley EH, Samir P, Dineley KT, Vargas G, Zhou J, Cisneros I, Stephens R, Laezza F. J Neroinflammation. 2023, 20(1), 306-339.
- Molecular, Metabolic, and Subcellular Mapping of the Tumor Immune Microenvironment via 3D Targeted and Non-Targeted Multiplex Multi-omics Analyeses. Ferri-Borgogno S, Burks JK, Seeley EH, McKee TD, Stolley DL, Basi AV, Gomez JA, Gamal BT, Ayyadhury S, Lawson BC, Yates MS, Birrer MJ, Lu KH, Moc SC. Cancers. 2024, 16(5), 846-868.
- In Vitro Evaluation of the Percutaneous Absorption of Progesterone in Anhydrous Permeation-Enhancing Base using the Franz Skin Finite Does Model and Mass Spectrometry. Banov D, Song G, Ip K, Seeley EH, Linehan ST, Bassani I, Ferron G, Bassani AS, Valdez BC. Arch. Dermatol Res. 2024, 316, 291.
- Spatial Multiplexing and Omics. Carsten JL, Krishnan SN, Rao A, Sorace AG, Seeley EH, Ferri-Borgogno S, Burks JK. Nat Rev Methods Primers. 2024, 4, 54.
- Evaluating Drug Distribution in Rat Lung by Mass Spectrometry Imaging after Dry Powder Insufflation: Comparison of Jet-Milling, Spray-Drying, and Thin Film Freezing. Moon C, Maier EY, Seeley EH, Warnken ZN, Behrend-Keim B, Yanwinitchai S, Mota M, Williams III RO. J Drug Deliv Sci Technol. 2024, 101(A), 106206.
- Inhibition of Hepatic Oxalate Overproduction Ameliorates Metabolic Dysfunction-Associated Steatohepatitis. Das S, Finney AC, Anand SK, Rohilla S, Liu Y, Pandey N, Ghrayeb A, Kumar D, Nunez, K, Liu Z, Arias F, Zhao Y, Pearson-Gallion BH, McKinney MP, Richard KSE, Gomez-Vidal JA, Abdulla CS, Cockerham ED, Eniafe J, Yurochko AD, Tarek Magdy, Pattillo CB, Kevil CG, Razani B, Bhuiyan MS, Seeley EH, Galliano GE, Wei B, Tan L, Mahmud I, Surakka I, Garcia-Barrio MT, Lorenzi PL, Gottlieb E, Salido E, Zhang J, Orr AW, Liu W, Diaz-Gavilan M, Chen YE, Dhanesha N, Thevenot PT, Cohen AJ, Yurdigal Jr A, Rom O. Nat Metab. 2024, 6, 1932-1962.
- Comformational Characterization of Peptides and Proteins by 193 nm Ultraviolet Photodissociation in the Collision Cell of a Trapped Ion Mobility Spectrometry-Time-of-Flight Mass Spectrometer. Butalewicz JP, Escobar EE, Wootton CA, Theisen A, Park MA, Seeley EH, Brodbelt JS. Anal Chem. 2024, 96(41), 16154-16161.
Presentations and Posters
- Reduced Hemoglobin Signal and Improved Detection of Low Adundance Proteins in Blood-Rich Tissues for MALDI Mass Spectrometry Imaging. Lin M, Eberlin LS, and Seeley EH. Presented at the 2020 IMSI Poster Gala. December 15-17, 2020. Virtual.
- Improved Diagnosis of Melanocytic Lesions using Mass Spectrometry Imaging. Seeley EH. Presented as part of the HTXNext Webinar Series. June 9, 2021.
- Mass Spectrometry Imaging Enables Localization of Immuno- and Targeted Therapies Delivered Transarterially for Hepatocellular Carcinoma. Seeley EH, Munoz NM, Avritscher R, Koppolu B, Ramkumar N, Johnson R, Kangas S, Sheth RA. Presented at 69th ASMS Conference on Mass Spectrometry and Allied Topics. November 2021. Philadelphia, PA.
- New Sample Preparation Strategies for MALDI Imaging of Clinical Samples. Seeley EH. Bruker/Technology Networks Webinar. December 9, 2021.
- Metabolic Imaging of O-linked N-Acetylglucosamine using On-Tissue Hydrolysis and MALDI. Escobar EE, Seeley EH, Brodbelt JS. Presented at 70th ASMS Conference on Mass Spectrometry and Allied Topics. June 2022. Minneapolis, MN.
- Mass Spectrometry Imaging for Protein Localization and Characterization in Thermoembolized Hepatic Porcine Tissue. Porter JE, Stolley D, Cressman ENK, Seeley EH. Presented at 70th ASMS Conference on Mass Spectrometry and Allied Topics. June 2022. Minneapolis, MN.
- Optimization and Investigation of Protein Molecular Signatures in Endometriosis Tissues by Mass Spectrometry Imaging. Lin M, Seeley EH, Ledet S, Salazar C, Breen MT, Eberlin LS. Presented at 70th ASMS Conference on Mass Spectrometry and Allied Topics. June 2022. Minneapolis, MN.
- Maximizing Data Coverage with Sequential Imaging of a Single Tissue Section. Seeley EH, Escobar EE, Brodbelt JS. Presented at 71st ASMS Conference on Mass Spectrometry and Allied Topics. June 2023. Houston, TX.
- Mass Spectrometry Imaging Reveals Molecular Changes Associated with Aging in Pancreatic Cancer. Seeley EH, Min J, Burks JK, Guerrero PA, Maitra A. Presented at CPRIT Innovations IV. October 2023. Galveston, TX.
- Combining Drug and Targeted Protein Imaging to Uncover Molecular Changes Associated with Cancer Treatment. Seeley EH, Kita CA, Yagnik GB, Rothschild KJ, Lim MJ, Sheth RA. Presented at 72nd ASMS Conference on Mass Spectrometry And Allied Topics. June 2024. Anaheim, CA.
- Fast Lipid Analysis of Lipid A Coupled with Tandem Mass Spectrometry. Zuercher KS, Seeley EH, Brodbelt JS. Presented at 72nd ASMS Conference on Mass Spectrometry And Allied Topics. June 2024. Anaheim, CA.
- Multi-Site Reproducibility Trial of MALDI-IHC Multiplexed Targeted Protein Imaging using a 33-Organ Tissue Microarray. Shafer CC, Holbrook JH, Kita CA, Yagnik GB, Lim MJ, Rosthchild KJ, Stumpo KA, Seeley EH, Neumann EK, Hummon AB. Presented at 72nd ASMS Conference on Mass Spectrometry And Allied Topics. June 2024. Anaheim, CA.
- Spatial Mapping of Ether Lipids in Tissue via MALDI TIMS Imaging Mass Spectrometry: Characterization of Biomarkers of Peroxisomal Disorders. Campbell MJ, Seeley EH, Brodbelt JS. Presented at 72nd ASMS Conference on Mass Spectrometry And Allied Topics. June 2024. Anaheim, CA.
- Spatial Multi-Omics Investigation of High-Grade Serous Ovarian Cancer Tumor Microenvironment Provides Insight into Minimal Residual Disease and Instinsic Chemoresistance. Seeley E, Gamal B, Patterson NH, Zhang W, Mantas MJQ, Ly A, Verbeeck N, Claesen M, Jazaeri A, Burks J, Mok S, Ferri-Borgogno S. Presented at 72nd ASMS Conference on Mass Spectrometry And Allied Topics. June 2024. Anaheim, CA.