LeVieux, J.A., Medellin, B.P., Johnson, W.H. Jr., Erwin, K., Li, X., Johnson, W.H. Jr., YJ. Zhang *, and C.P* Whitman. “Structural Characterization of the Hydratase-Aldolases, NahE, and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily..” Biochemistry, 57, 25, Pp. 3524-3536 . Publisher's Version

Irani, S, Naowarojna, N., Tang, Y., Kathuria, K.R., Wang, S. A., Dhembi, A., Lee, N., Yan, W., Lyu, H., Costello, C.E., P. Liu, and Y. J. Zhang. “Snapshots of C-S cleavage in Egt2 reveals substrate specificity and reaction mechanism..” Cell Chemical Biology, 25, 5, Pp. 519-529.e4. . Publisher's Version

Burkholder, N.T., Medellin, B.P., Irani, S, Matthews, W.M., Showalter, S.A., and Y. J. Zhang. “Chemical tools for studying the impact of cis/trans prolyl isomerization on RNA polymerase II CTD phosphatase activity and specificity..” In Methods in Enzymology, 607: Pp. 269-297.

Stack, T.M.M., Li, X., Johnson, W.H. Jr., YJ Zhang, and C.P. Whitman. “Inactivation of 4-Oxalocrotonate Tautomerase by 5-Halo-2-hydroxy-2,4-pentadienoates..” Biochemistry, 57, 6, Pp. 1012-1021. Publisher's Version

Davidson, R., Baas, B., Akiva, E., Holliday, G.L., Polacco, B.J., LeVieux, J.A., Pullara, C.R., YJ Zhang, C.P Whitman, and P.C. Babbitt. “A Global View of Structure-Function Relationships in the Tautomerase Superfamily..” JBC, 293, 7, Pp. 2342-2357. Publisher's Version

LeVieux, J.A., Baas, B., Kaoud, T.S., Davidson, R., Babbitt, P.C., YJ Zhang, and C.P. Whitman. “Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily..” Arch. Biophy. Biochem. , 636, Pp. 50-56. . Publisher's Version

Lee, N., Romain, G., Yan, W., Watanabe, M., Charab, W., Todorova, B., Lee J., Triplett, K., Donkor, M., Lungu, O.I., A. Lux, Marshall, N., Lindorfer, M.A., Goff, O.R., Balbino, B., Kang, T.H., Tanno, H., G Delidaki, Alford, C., R.P. Taylor, Nimmerjahn, F., Varadarajan, N., Bruhns, P., Y. J. Zhang, and G. Georgiou. “IgG Fc Domains that bind C1q but not effector Fcgamma receptors delineate that significance of complement-mediated cell cytotoxicity and phagocytosis in antibody function..” Nature Immunology. , 18, 8, Pp. 889-898. Publisher's Version

Gibbs, E.B., Y Lu, B Portz, M. J. Fisher, Medellin, B.P., Laremore, T.N., Zhang, L., Gilmour, D.S., and S.A Showalter. “Phosphorylation Induces Sequence-Specific Conformational Switches in the RNA Polymerase II C-Terminal Domain..” Nature Communications. , 8, Pp. 15233. Publisher's Version

Portz, B., Lu, Gibbs, E.B., Mayfield, J.E., Mehaffey, M.R., Zhang, L., Brodbelt, J.S., Showalter, S.A., and D.S. Gilmour. “Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain..” Nature Communications., 8, Pp. 15231. Publisher's Version

Yan, W., Georgiou, G., Stone, E., and Y. J. Zhang. “Structural Snapshots of an Engineered Cystathionine-gamma-lyase Reveal the Critical Role of Electrostatic Interactions in the Active Site..” Biochemistry, 56, 6, Pp. 876-885. Publisher's Version

Cramer, S., Saha, A., Tadi, S., Tiziani, S., Yan, W., Triplett, K., Lamb, C., S. Alters, Johnson, W.H. Jr., Zhang, L., DiGiovanni, J., Georgiou, G., and E. Stone. “Systemic depletion of serum L-Cyst(e)ine with an engineered human enzyme induces the production of reactive oxygen species and suppresses tumor growth in mice..” Nature Medicine, 23, 1, Pp. 120-127. Publisher's Version

Mayfield, J.E., Robinson, M.R., Cotham, V.C., Irani, S, Matthews, W.M., Ram, A., Gilmour, D.S., Cannon, J.R., YJ Zhang *, and J.S Brodbelt *. “Mapping the phosphorylation pattern of Drosophila RNA polymerase II carboxyl-terminal domain using ultraviolet photodissociation mass spectrometry..” ACS Chemical Biology, 12, 1, Pp. 153-162. Publisher's Version

Mayfield, J.E., Burkholder, N.T., and Y. J. Zhang. “Dephosphorylating eukaryotic RNA polymerase II..” BBA Proteins Proteom. , 1864, 4, Pp. 372-387. Publisher's Version

Irani, S, Yogesha, S.D., Mayfield, J.E., Zhang, L., Zhang, L., Matthews, W.M., Nie, G., Prescott, N., and Y. Zhang. “Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase..” Science Signaling, 9, Pp. 417. Publisher's Version

Li, X., Irani. S., Crutchfield, A., Hodge, K., Matthews, W.M., Patel, P., Zhang *, YJ, and E. Stone *. “Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages..” Biochemistry, 55, 6, Pp. 960-969. Publisher's Version

LeVieux, J.A., Johnson, W.H. Jr., Erwin, K., Li, X., Y. J. Zhang, and C.P. Whitman. “The bacterial catabolism of polycyclic aromatic hydrocarbons: Characterization of three hydratase-aldolase-catalyzed reactions..” Perspective in Science., 99, Pp. 33-41. Publisher's Version

Mayfield, J.E., Fan, S., Wei, S., Zhang, L., Li, X., Ellington, A.D., Etzkorn, F.A., and Y. J. Zhang. “Chemical tools to decipher regulation of phosphatases by proline isomerization on eukaryotic RNA polymerase II..” ACS Chemical Biology, 10, 10, Pp. 2405-14. Publisher's Version

Wei, S., Kozono, S., Kats, L., Nechama, M., Li, X., Guarnerio, J., Luo, M., You, M.H., Y. Yao, Kondo, A., Hu, W., Bozkurt, G., Moerke, N., Cao, S., Reschke, M., Chen, J.*, Rego, E.M., Lo-Coco, F., L.C. Cantley, Lee, N., Wu, H., YJ Zhang, Pandolfi, P.P., Zhou, X.Z., and K.P. Lu. “Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer..” Nature Medicine, 21, Pp. 457-466. Publisher's Version

Chen, J.*, Li, X., Sultana, R., You, M.H., Kondo, A., Shahpasand, K., Kim, B., Luo, M., M Nechama, Lin, B., Yao, Y., Lee, N., Zhou, X.Z., Swomley, A., D Butterfield*, YJ Zhang *, and KP Lu*. “Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease..” Neurobiol. Dis. , 76, Pp. 13-23. Publisher's Version

He, Y., Guo, Y., Yu, X., Wu, H., Gunawan, A.M., YJ Zhang, Dixon, J.E., and Z.Y. Zhang. “A potent and selective inhibitor for the UBLCP1 proteasome phosphatase..” Bioorg. Med. Chem., 23, 12, Pp. 2798-2809. . Publisher's Version