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2023
(80), Y. Jessie Zhang, and Philip A. Cole
. “
Editorial: Mechanistic Biology
.” Current Opinion of Chemical Biology, 74.
(79), Lancaster EB, Johnson WH Jr, LeVieux JA, Hardtke HA, Zhang YJ, and Whitman CP.
“
A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway
.” Arch Biochem Biophys., 733, Pp. 109471.
Publisher's Version
2022
(78), Blazeck J, Karamitros CS, Ford K, Somody C, Qerqez A, Murray K, Burkholder NT, Marshall N, Sivakumar A, Lu WC, Tan B., Lamb C, Tanno Y, Yemeny MS, Zhang M, McGovern K, Kumada Y, Zhang YJ, Manfredi M, Johnson KA, D'Arcy S, Stone E, and Georgiou G
. “
Bypassing evolutionary dead-ends and switching the rate-limiting step of a human immunotherapeutic enzyme
.” Nature Catalysis, 5, Pp. 952–967.
Publisher's Version
(77), Kim W, Chen TY, Cha L, Zhou G, Xing K, Canty NK, Zhang Y *(co-corresponding), and Chang WC
. “
Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate
.” Nature Communication, 13, 5343.
Publisher's Version
(76), d’Oelsnitz S, Kim W, Burkholder NT, Javanmardi K, Thyer R, Zhang Y, Alper H, and Ellington AD
. “
Directed Evolution of a Generalist Biosensor Accelerates Alkaloid Pathway Engineering
.” Nature Chemical Biology.
Publisher's Version
(75), E.B. Lancaster, W.J. Yang, W.H. Johnson, B-J. Baas, Y. J. Zhang, and C.P. Whitman
. “
Kinetic, Inhibition, and Structural Characterization of a Malonate Semialdehyde Decarboxylase Homolog from Calothrix sp. PCC 6303: A Gateway to the non-Pro1 Tautomerase Superfamily Members
.” Biochemistry.
Publisher's Version
(74), Lu H, Diaz DJ, Czarnecki NJ, Zhu C, Kim W, Shroff R, Acosta DJ, Alexander B, Cole HO, Zhang YJ, Lynd NA, Ellington AD, and Alper HS
. “
Machine learning-aided engineering of PET hydrolase for PET depolymerization.
.” Nature, 604, Pp. 662–667.
Publisher's Version
(73), Polyanskaya SA, Moreno RY, Lu B, Feng R, Yao Y, Irani S, Klingbeil O, Yang Z, Wei Y, Demerdash OE, Benjamin LA, Weiss MJ, Zhang YJ, and Vakoc CR
. “
The SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
.” Cell Report, 38, 2, Pp. 110233.
Publisher's Version
(72), BP Medellin, WJ Yang, S Konduri, J Dong, S Irani, HY Wu, WL Matthews, Z-Y Zhang, D Siegel, and Y Zhang
. “
Targeted Covalent Inhibition of Small CTD Phosphatase-1 to Promote the Degradation of REST Transcription Factor in Human Cells
.” Journal of Medicinal Chemistry , 65, Pp. 507-519.
Publisher's Version
2021
(71), F Meng, Z Yu, D Zhang, S. Chen, H Guan, R Zhou, Q Wu, Q Zhang, MK Venkat Ramani, S Liu, B Yang, X-Q Ba, J Zhang, J Huang, X Bai, J Qin, X-H Feng, Ouyang, S, YJ Zhang, T Liang, and P Xu
. “
Induced phase separatation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
.” Molecular Cell, 81, 20, Pp. 4147-4164.
Publisher's Version
(70), W Kim, B LeBlanc, WL Matthews, Z-Y Zhang, and YJ Zhang
. “
Advancements in Chemical Biology Targeting the Kinases and Phosphatases of RNA Polymerase II-mediated Transcription
.” Current Opinion in Chemical Biology, 63, Pp. 68-77.
Publisher's Version
(69), BM LeBlanc, Moreno, RY, Escobar, E.E., M.K. Venkat Ramani, J.S Brodbelt, and Y Zhang
. “
What’s all the phos about? Insights into the phosphorylation state of the RNA polymerase II C-terminal domain via mass spectrometry
.” Royal Society of Chemistry Chemical Biology, 2, Pp. 1084-1095.
Publisher's Version
(68), EE Escobar, MK Venkat Ramani, Y Zhang, and JS Brodbelt
. “
Parallel Reaction Monitoring of RNA polymerase II Carboxy-terminal Domain Phosphorylation using 193 nm Ultraviolet Photodissociation Mass Spectrometry
.” JACS, 143, 22, Pp. 8488-8498.
Publisher's Version
(67), BJ Bass, Medellin, B.P., J.A. LeVieux, K Erwin, E.B. Lancaster, W.H Johnson, T.S. Kaoud, R.Y. Moreno, de Ruijter, M., P.C. Babbit, Y. J. Zhang, and C.P. Whitman
. “
Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications
.” Biochemistry.
Publisher's Version
(66), MKV Ramani, W Yang, S Irani, and Y Zhang
. “
Simplicity is the Ultimate Sophistication — Cross-talk of Post-translational Modifications on the RNA Polymerase II
.” JMB, 63, Pp. 68-77.
Publisher's Version
(65), Zhou R, Wu Q, Wang M, S Irani, Li X, Zhang Q, Meng F, Liu S, Zhang F, Wu L, Lin X, Wang X, Zou J, Song H, Qin J, Liang T, Feng X-H, Zhang YJ, and Xu P
. “
The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration
.” PLoS Biol, 19, 2, Pp. e3001122.
Publisher's Version
2020
Gong S, Kirmizialtin S, Chang A, Mayfield JE, Zhang YJ, and Johnson KA
. “
Kinetic and thermodynamic analysis defines roles for two metal ions in DNA polymerase specificity and catalysis.
.” JBC.
Publisher's Version
Ramani M.K.V, Escobar E.E., Irani S., Mayfield JE, Moreno RY, Butalewicz, J., Cotham V.C, Wu H., Tadros M, Brodbelt JS, and Zhang YJ
. “
Structure Motif for CTD kinase Specificity on RNA polymerase II during Eukaryotic Transcription
.” ACS Chemical Biology.
Publisher's Version
Aggarwal K, Kuka TP, Banik M, Medellin BP, Ngo CQ, Xie D, Fernandes Y, Dangerfield TL, Ye E, Bouley B, Johnson KA, Zhang YJ, Eberhart JK, and Que EL.
“
Visible Light Mediated Bidirectional Control Over Carbonic Anhydrase Activity in Cells and in Vivo Using Azobenzene Sulfonamides
.” J. Am. Chem. Soc.
Publisher's Version
Mayfield J.E., Irani S., and Zhang Y.J.
“
Electrophoretic Mobility Shift Assay of in vitro Phosphorylated RNA Polymerase II Carboxyl-terminal Domain Substrates.
.” Bioprotocol, 10, 12.
Publisher's Version
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